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Interstitial Nephritis

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Interstitial nephritis is the inflammation of the spaces between the kidney tubules. The main function of the kidneys is to filter the waste products from the blood. The kidney tubules reabsorb water and important organic substances from the kidney filtrate and secrete the waste products into the filtrate to be removed by urination. Swelling of these tubules can lead to malfunctioning of the kidneys. Interstitial nephritis can be acute (temporary) or chronic (long-lasting). Acute interstitial nephritis can be caused by:

  • Infections such as Streptococcal, herpes , mumps, hepatitis C , HIV

  • Medicines such as antibiotics, anti-ulcer drugs, NSAIDs (Nonsteroidal Anti-inflammatory Drugs) and diuretics

  • Autoimmune disorders such as systemic lupus erythematosus which causes your child’s immune system to attack the kidneys

In children, most often, the cause of interstitial nephritis is infection.

When to seek expert advise

Make an appointment for consultation with our internationally trained staff at the Children's Hospital Service Line at The Aga Khan University Hospital the only internationally accredited hospital in Pakistan, if you notice any of the above mentioned symptoms in your child.

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Disclaimer

The information provided on our website is for educational purposes and not intended to be a substitute for medical advice, diagnosis or treatment. You should always seek the advice of your doctor or other healthcare professional provider.