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Interstitial Nephritis

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Interstitial nephritis is the inflammation of the spaces between the kidney tubules. The main function of the kidneys is to filter the waste products from the blood. The kidney tubules reabsorb water and important organic substances from the kidney filtrate and secrete the waste products into the filtrate to be removed by urination. Swelling of these tubules can lead to malfunctioning of the kidneys. Interstitial nephritis can be acute (temporary) or chronic (long-lasting). Acute interstitial nephritis can be caused by:

  • Infections such as Streptococcal, herpes , mumps, hepatitis C, HIV

  • Medicines such as antibiotics, anti-ulcer drugs, NSAIDs (Nonsteroidal Anti-inflammatory Drugs) and diuretics

  • Autoimmune disorders such as systemic lupus erythematosus which causes the immune system to attack the kidneys

In children, most often, the cause of interstitial nephritis is infection.

When to seek expert advice

Make an appointment for consultation with the Section of Nephrology or with a paediatric nephrologist at the Department of Paediatrics, if you notice any of the above mentioned symptoms in you or your child.

Disclaimer

The information provided on our website is for educational purposes and not intended to be a substitute for medical advice, diagnosis or treatment. You should always seek the advice of your doctor or other healthcare professional provider.

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