Impetigo usually clears up on its own in two to three weeks but you must keep your child away from company to avoid the spread of infection. Seeing your child in discomfort and isolated is never easy. A course of antibiotics, including creams or ointment applied directly to the sores or taken orally, can shorten the course of the disease. Make sure to complete the course of antibiotics so that the infection does not come back. You can also wash the infected areas gently with mild soap to remove the crust and drainage.